1.
Arch Pharm (Weinheim)
; 347(2): 134-41, 2014 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24272912
RESUMO
Montmorillonite K10 impregnated with copper dichloride and potassium iodide (CuCl2 /KI/K10) was used as catalyst in the cycloaddition of azides and propargylnucleobases, to provide the corresponding 1,4-disubstituted 1,2,3-triazoles in good yield. All compounds 16-23 were evaluated for their antiviral activity in vitro. Compound 18 showed moderate inhibition against influenza virus A (H3N2).